Asthma or asthma-COPD overlap syndrome? - Reply

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The Asthma-COPD Overlap Syndrome.

Although in textbooks asthma and chronic obstructive pulmonary disease (COPD) are viewed as distinct disorders, there is increasing awareness that many patients have features of both. This article reviews the asthma-COPD overlap syndrome.

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The Asthma-COPD Overlap Syndrome

Asthma and Chronic Obstructive Pulmonary Disease (COPD) are pulmonary disorders characterized by various degrees of airflow limitation, inflammation and tissue remodeling. Bronchial asthma, an allergic disease that develops in childhood, is physiologically characterized by reversible airflow obstruction. It has an episodic course and a generally favorable prognosis, as it responds well to anti-...

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The asthma - COPD overlap syndrome ( ACOS ) : hype or reality ?

Asthma and chronic obstructive pulmonary disease (COPD) are chronic diseases with high prevalence in the general population. Asthma affects 25 million Americans (18 million adults and 7 million children) (1), while about 14.2 million Americans are diagnosed with COPD and 9.8 million are estimated to have COPD that is undiagnosed (2, 3). A variable degree of airway inflammation, airway obstructi...

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Heterogeneity of asthma–COPD overlap syndrome

Many patients suffering from asthma or COPD have overlapping features of both diseases. However, a phenotypical approach for evaluating asthma-COPD overlap syndrome (ACOS) has not been established. In this report, we examined the phenotypes in patients with ACOS. Patients diagnosed with ACOS between 2011 and 2015 were identified and classified into four phenotype groups. Group A was composed of...

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Asthma-COPD overlap syndrome and precision medicine.

Differentiation of asthma and chronic obstructive pulmonary disease (COPD) in symptomatic patients has been extremely difficult clinically in many instances. This situation led to the formulation of the so-called “Dutch hypothesis” in 1961,1 cited by Christenson.2 The theory postulates that obstructive lung disease occur in a continuum, with asthma and COPD being expressions of the same disease...

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ژورنال

عنوان ژورنال: Respirology

سال: 2017

ISSN: 1323-7799

DOI: 10.1111/resp.12992